Product Description:
Therapeutic group:
- Vivisac Plus is a combination of two active ingredients, irbesartan and hydrochlorothiazide. Irbesartan belongs to a group of medicines known as angiotensin II receptor antagonists. Angiotensin II is a substance produced in the body that binds to receptors in blood vessels, causing them to tighten and leading to an increase in blood pressure. Irbesartan prevents angiotensin II from binding to these receptors, causing them to relax.
- Hydrochlorothiazide is one of a group of medicines (called thiazide diuretics) that cause an increase in the amount of urine excreted and thus lower blood pressure.
- The two active ingredients in Vivisac Plus work together to lower blood pressure more than if either active ingredient was given alone.
Therapeutic uses:
- Vivisac Plus is used to treat high blood pressure when treatment with irbesartan or hydrochlorothiazide alone does not provide adequate control of blood pressure.
Directions for use:
- Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
Dosage:
- The recommended dose of Vivisac Plus is one or two tablets daily. Vivisac Plus is usually prescribed by a doctor when previous treatment has not reduced blood pressure sufficiently.
- Your doctor will advise you on how to switch from your previous treatment to Vivisac Plus.
- How to take Vivisac Plus: Vivisac Plus is for oral use. The tablets should be swallowed with a sufficient amount of liquid (e.g., one glass of water). You can take Vivisac Plus regardless of food intake. The dividing line on the Vivisac Plus 5/150 mg tablet is not for dividing the tablet into equal doses. It is important that you continue taking Vivisac Plus until your doctor tells you otherwise.
- The maximum blood pressure lowering effect should be achieved within 6-8 weeks after the start of treatment.
- Vivisac Plus should not be given to children.
- Vivisac Plus should not be given to children under 18 years of age. If a child swallows any tablets, contact your doctor immediately.
- A. If you take more Vivisac Plus than you should
- If you accidentally take too many tablets, contact your doctor immediately.
- b. If you forget to take Vivisac Plus
- If you accidentally miss your daily dose, just take the next dose as usual. Do not take a double dose to make up for a missed dose. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
- A. If you stop taking Vivisac Plus
- Do not stop taking Vivisac Plus tablets unless your doctor tells you to. You should stop taking Vivisac Plus tablets gradually, especially if you are taking a high dose, unless your doctor tells you otherwise. Stopping treatment suddenly may cause sudden effects such as increased heart rate.
- Heart and high blood pressure. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Warnings and Precautions:
Do not take Vivisac Plus
- If you are allergic to irbesartan or any of the other ingredients of this medicine.
- If you are allergic to hydrochlorothiazide or any other sulfonamide-derived medicine.
- - During the last six months of pregnancy (it is best to avoid taking Vivisac Plus at the beginning of pregnancy.)
- If you have severe liver or kidney problems.
- If you have difficulty producing urine.
- If your doctor decides that you have persistently high levels of calcium or potassium in your blood.
- You have diabetes or impaired kidney function and are being treated with a blood pressure lowering medicine containing aliskiren.
Precautions when using Vivisac Plus
- Talk to your doctor before taking Vivisac Plus if any of the following apply to you:
- If you suffer from excessive vomiting or diarrhea.
- If you have kidney problems or have had a kidney transplant.
- If you have heart problems.
- If you have diabetes.
- If you have systemic lupus erythematosus (also known as lupus or systemic lupus erythematosus).
- If you have primary aldosteronism (a condition involving high production of the hormone aldosterone, which causes sodium retention and, therefore, increased blood pressure).
- If you are taking any of the following medications used to treat high blood pressure:
- Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril, lisinopril, ramipril), especially if you have kidney problems related to diabetes.
- Aliskiren
- Your doctor may check your kidney function, blood pressure, and the amount of electrolytes (for example, potassium) in your blood at regular intervals.
- You must tell your doctor if you think you are (or may become) pregnant. Vivisac Plus is not recommended for use in early pregnancy and can cause serious harm to your baby after 3 months of pregnancy if used at this stage.
You should also tell your doctor:
- If you are on a low salt diet.
- If you have signs such as abnormal thirst, dry mouth, general weakness, drowsiness, muscle pain or cramps, nausea, vomiting, or an abnormally fast heartbeat that may indicate an overdose of hydrochlorothiazide.
- If you experience increased skin sensitivity to the sun with symptoms of sunburn (such as redness, itching, swelling, blisters) that occur more quickly than usual.
- If you are going to have surgery or be given anesthesia.
- If you experience changes in your field of vision or blurred vision in one or both eyes while taking Vivisac Plus , this could be a sign that you are developing glaucoma, an increase in pressure in your eyes. You should stop taking Vivisac Plus and seek medical attention.
- The hydrochlorothiazide in this medication can produce a positive result on an anti-doping test.
Children and adolescents:
- Vivisac Plus should not be used in children and adolescents (under 18 years of age).
C. Drug interactions from taking this product with any other medications, herbs or nutritional supplements
- Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Diuretics such as hydrochlorothiazide contained in Vivisac Plus may affect other medicines. Preparations containing lithium should not be taken with Vivisac Plus without close medical supervision.
- Your doctor may need to change your dose and/or take other precautions:
- If you are taking angiotensin-converting enzyme inhibitors or aliskiren.
You may need blood tests if you are taking:
- Potassium supplements.
- Salt substitutes containing potassium.
- Potassium-sparing drugs (such as some diuretics).
- Some laxatives.
- Medications to treat gout.
- Vitamin D therapeutic supplements.
- Heart rhythm control medications.
- Medications to treat diabetes (oral medications or insulin.
- Carbamazepine (a medicine used to treat epilepsy.)
- It is also important to tell your doctor if you are taking other medications to lower blood pressure, steroids, cancer medications, painkillers, arthritis medications, or cholestyramine and colestipol resins used to lower blood cholesterol.
Take Vivisac Plus tablets with food and drink.
- Vivisac Plus can be taken regardless of meals. Because of the presence of hydrochlorothiazide in Vivisac Plus and if you drink alcohol while taking this medicine, you may experience an increased feeling of dizziness upon standing, especially when getting up from a sitting position.
Pregnancy and breastfeeding
- Pregnancy You should tell your doctor if you think you are (or may become) pregnant. Usually, your doctor will advise you to stop taking Vivisac Plus before you become pregnant or as soon as possible after you find out you are pregnant and advise you to use another medicine instead of Vivisac Plus. Vivisac Plus is not recommended in early pregnancy and should not be taken after the first three months of pregnancy, as it may cause serious harm to your baby if used after the third month of pregnancy.
breastfeeding
- Tell your doctor if you are breastfeeding or about to start breastfeeding. Vivisac Plus is not recommended for use by breastfeeding mothers. Your doctor may choose another treatment if you wish to breastfeed, especially if your baby is a newborn or was born prematurely.
Driving and using machines:
- No studies have been conducted to determine the effect on the ability to drive and use machines. Vivisac Plus is unlikely to affect your ability to drive or use machines. However, dizziness or fatigue may occasionally occur while treating high blood pressure. If you experience such symptoms, you should talk to your doctor before attempting to drive or use machines.
Important information about one of the ingredients in Vivisac Plus
- Vivisac Plus contains lactose. If you have been told by your doctor that you have an intolerance to some sugars (such as lactose), contact your doctor before taking this medicine.
the components:
The active ingredient is: Irbesartan and Hydrochlorothiazide.
- Vivisac Plus : 12.5/150 Each coated tablet contains 150 mg Irbesartan and 12.5 mg Hydrochlorothiazide.
Other ingredients are:
- Lactose, croscarmellose sodium, starch, hypromellose, microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate, Opadry white, iron oxide red, and iron oxide yellow.
What is the pharmaceutical form of Vivisac Plus, its description and package size?
- Pharmaceutical form: coated tablets
Physical description of Vivisac Plus:
- Vivisac Plus : 12.5/150 tablets, light pink, oblong, biconvex, split on one side and smooth on the other.
- Vivisac Plus tablets: Packed in aluminum and PVC/PVDC blisters, then packed in cartons with a folded leaflet.
- Package size: 30 coated tablets (10 tablets/strip, 3 strips/packet).
