Tevetin-Plus 600/12.5 mg 28 tablets
Eprosartan with Hydrochlorothiazide 600/12.5 mg Tablets
What is Eprosartan with Hydrochlorothiazide and what is it used for?
This medicine contains two active ingredients:
• Eprosartan belongs to a group of medicines called angiotensin II receptor antagonists. Eprosartan works by blocking the action of a substance called angiotensin II, which helps relax blood vessels and lower blood pressure.
• Hydrochlorothiazide belongs to a group of medicines known as diuretics or water pills. It works by making your kidneys pass more water and salt. This helps reduce high blood pressure and some forms of swelling.
This medicine is used to treat high blood pressure.
What you need to know before using eprosartan with hydrochlorothiazide:
Do not use eprosartan with hydrochlorothiazide.
• If you are allergic (hypersensitive) to eprosartan with hydrochlorothiazide or any of the other ingredients in these tablets
• If you are allergic to any medicine containing sulfonamides.
• If you are more than 3 months pregnant. (It is also best to avoid taking eprosartan with hydrochlorothiazide in early pregnancy.)
• If you have serious liver problems
• If you have damaged blood flow to the kidneys or severe spasms in one functioning kidney
• If you have diabetes or impaired kidney function and are being treated with a blood pressure lowering medicine containing aliskiren.
Warnings and Precautions:
You should tell your doctor if:
• If you think you are (or may become) pregnant. Eprosartan is not recommended for use in early pregnancy and should not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage.
• If you are dehydrated or have low salt levels (because you are on a low-salt diet, taking water tablets, or have diarrhea or vomiting). These conditions must be corrected before you start taking eprosartan with hydrochlorothiazide.
• If you know you have elevated potassium levels in your blood
• If you have heart disease, for example, heart valve disease, enlarged heart, or weak heart muscle (heart failure).
• If you have severe kidney problems, have had a kidney transplant, or need dialysis
• If you have narrowing or blockage in the blood vessels leading to your kidney(s)
• If you have any other liver problems
• If you have gout
• If you have a condition affecting the adrenal gland (hyperaldosteronism)
• If you are of African-Caribbean descent, eprosartan may be less effective in lowering your blood pressure.
• If you are taking any of the following medications used to treat high blood pressure:
- ACE inhibitors (eg, enalapril, lisinopril, ramipril), especially if you have kidney problems related to diabetes
Aliskiren
Other medications and eprosartan:
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
This includes medications obtained without a prescription, or the following:
• Other medications for high blood pressure, especially ACE inhibitors, medications containing aliskiren, or diuretics (water or fluid tablets)
• Medications that affect potassium levels
• Nonsteroidal anti-inflammatory drugs (NSAIDs) and medications used to relieve pain, swelling, and other symptoms of inflammation
• Diabetes medication
• Heart medications
• Gout medication
• Muscle relaxants
• Medicines used to treat mental illnesses and epilepsy.
• Parkinson's medication
• Laxatives, corticosteroids, and adrenocorticotropic hormone (ACTH)
• Cancer medicine
• Calcium and vitamin D supplements
Your doctor may need to change your dose and/or take other precautions:
• If you are taking an ACE inhibitor or aliskiren
How to use eprosartan with hydrochlorothiazide:
Always take this medicine exactly as your doctor or pharmacist has told you. Consult your doctor or pharmacist if you are not sure.
Swallow the tablets whole with water once a day with or without food.
Try to take your tablets at the same time each day.
Adults
The recommended dose is one tablet of eprosartan with hydrochlorothiazide once a day.
Use in children and adolescents
Children and adolescents under 18 years of age should not take eprosartan.
Patients with liver or kidney disease
Do not take eprosartan with hydrochlorothiazide if you have severe liver problems.
Possible side effects:
Stop using the product and seek immediate medical attention if:
• Swelling of the face, lips, tongue, or throat, which may cause difficulty breathing or swallowing.
How to store eprosartan with hydrochlorothiazide:
• Keep this medicine out of the sight and reach of children.
• Do not use this medicine after the expiry date printed on the carton, blister, or bottle after EXP. The expiry date refers to the last day of that month.
• Keep your tablets in a cool, dry place where the temperature stays below 25°C.
• Do not dispose of medications via wastewater or household waste. Ask your pharmacist how to dispose of medications you no longer use. These measures will help protect the environment.