Bisoprolol Fumarate 2.5 mg Film-coated Tablets
Why is bisoprolol used?
This medication is used to treat high blood pressure.
Do not use bisoprolol.
If you are allergic to the active ingredients or any of the other ingredients of this medicine.
Warnings and precautions
• You suffer from severe asthma or chronic lung disease.
• You have a severe problem with blood circulation in your extremities (such as Raynaud's syndrome), which may cause your fingers and toes to cramp or turn pale or blue.
• You have an untreated malignant tumor, which is a rare type of adrenal gland tumor.
• You have metabolic acidosis, a condition when there is too much acid in your blood.
• Acute heart failure or heart failure that suddenly becomes worse and/or that may require hospitalization
• Slow heart rate
• Severe drop in blood pressure
• A certain heart condition that causes a very slow heart rate or an irregular heartbeat.
• Cardiogenic shock, a severe acute heart condition that causes low blood pressure and circulatory failure.
If you have any of the following conditions:
• Diabetes
• Strict fasting (fasting from solid food)
• Certain heart conditions such as arrhythmia or severe chest pain while at rest (Prinzmetal's angina)
• Kidney or liver disease
• Circulation problems are less severe in your extremities.
• Less severe asthma or chronic lung disease
• History of scaly skin rash (psoriasis)
• Adrenal gland (medullary) tumor (pheochromocytoma)
Thyroid disorder
Possible side effects
Stop using the product and seek immediate medical attention if you experience throat tightness, swelling of the eyes, face, lips, or tongue, feel faint, or have difficulty breathing. Stop using the product if you experience hives or itching of the face or body.
Other medications Bisoprolol
• Blood pressure control medications or heart problems medications (such as amiodarone, amlodipine, clonidine, digitalis glycosides, diltiazem, disopyramide, felodipine, flecainide, lidocaine, methyldopa, moxonidine, phenytoin, propafenone, quinidine, rilmenidine)
• Antidepressants such as imipramine, amitriptyline, moclobemide
• Medications to treat mental illnesses, such as phenothiazines such as levomepromazine
• Medicines used for anesthesia during surgery (see also “Take care with bisoprolol tablets”)
• Medications used to treat epilepsy, for example, barbiturates such as phenobarbital.
• Some pain relievers (such as acetylsalicylic acid, diclofenac, indomethacin, ibuprofen, and naproxen)
• Asthma medications or medications used to treat nasal congestion
• Medications used for certain eye disorders such as glaucoma (increased pressure in the eye) or used to dilate the pupil
• Some medications to treat clinical shock (such as adrenaline, dobutamine, noradrenaline)
• Mefloquine, an antimalarial drug
• All of these medications, in addition to bisoprolol, may affect blood pressure and/or heart function.
• Rifampicin to treat infections
• Medicines for the treatment of severe headaches or migraines (ergotamine derivatives).
How to use bisoprolol
Treatment with bisoprolol fumarate tablets should be started at a low dose and gradually increased. Your doctor will decide how to increase the dose, which is usually done as follows:
• 1.25 mg bisoprolol fumarate once daily for one week
• 2.5 mg bisoprolol fumarate once daily for one week
• 3.75 mg bisoprolol fumarate once daily for one week
• 5 mg bisoprolol fumarate once daily for four weeks
• 7.5 mg bisoprolol fumarate once daily for four weeks
• 10 mg bisoprolol fumarate once daily for maintenance treatment.
The maximum recommended daily dose of bisoprolol fumarate is 10 mg.
How to store bisoprolol
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date printed on the carton. The expiry date refers to the last day of that month.
Do not store above 30°C. Keep the container tightly closed. Do not use if you notice any damage to the outer packaging.
Do not dispose of any medicines via wastewater or household waste.